A decreased incidence of PCF in patients undergoing regional flaps compared to those with free flaps was suggested but did not reach statistical significance (OR 0.51, 95% CI 0.21–1.24, P = 0.14) For the primary closure group, univariate followed by multivariate analysis was again performed using the same variables.
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Peri-operative factors predisposing to pharyngocutaneous fistula after total laryngectomy: analysis of a large multi-institutional patient cohort.
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