The effectiveness of computerised decision support on antibiotic use in hospitals: A systematic review.

ce Four studies reported on AMR.[ 36 , 46 , 48 , 54 ] In a study by Chan and co-workers, the rate of methicillin resistant Staphylococcus aureus (MRSA) decreased from 65–70% before the implementation of the antimicrobial approval system in 2003 to less than 60% in 2009.[ 46 ] Buising and co-workers showed a trend after the introduction of an antimicrobial approval system towards increased susceptibility of S . aureus to methicillin and increasing susceptibility of P seudomonas spp. isolates to both carbapenems and aminoglycosides.[ 48 ] Use and implementation Fifteen studies assessed aspects of the use and implementation of CDS, such as user satisfaction,[ 2 , 33 , 52 , 67 – 69 ] user uptake,[ 37 , 48 , 59 , 68 ] and acceptance of CDS recommendations.[ 38 , 46 , 50 , 51 , 59 , 70 , 71 , 72 ] Six studies showed improvement of user uptake and satisfaction.

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