Placental dysfunction is associated with altered microRNA expression in pregnant women with low folate status.

Mol Nutr Food Res · 2017 · PMC5573923 · PMID 28105727

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

failed to reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

miR222 was altered by low folate status, but this narrowly failed to reach statistical significance in this sample set ( p = 0.06).

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failed to reach significanceno p-value reported

This is likely to underlie the discrepancy in the array and PCR findings for miR222, whose upregulation narrowly failed to reach significance on the smaller sample set analyzed by array, and the fact that only two of the six miRNAs identified by array were successfully validated by QPCR.

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