Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs.

FEBS J · 2017 · PMC5575521 · PMID 28618157

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a clear trendno p-value reported

Differences between the mixed lipid and POPC were less apparent: a clear trend of increasing K M from liver lipid => mixed lipid => POPC is apparent by both assay methods (columns C, F, rows 7, 8, 9), but there was little difference in catalytic efficiency between the mixed lipid nanodiscs and the POPC nanodiscs (columns D, G, rows 7, 8).

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