We found near-significant or significant differences of total lysate β-Arrestin1 and ARHGAP21 between PTEN-expressing and -deficient cells [Caco-2 vs Sh PTEN ( Figure 1A,B ) and HCT116 vs PTEN -/- cells ( Figure 1—figure supplements 1 and 2 )].
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PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex.
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