Examination of overall survival in this group of stage 3 neuroblastoma patients univariately showed a trend, but not a significant difference ( p = 0.061), toward better survival in patients whose neuroblastomas displayed diffuse PTEN expression compared to focal or negative expression of this tumor suppressor gene (Figure 2B ).
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Association of high microvessel α<sub>v</sub>β<sub>3</sub> and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126.
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