Barely Significant
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Early presence of anti-angiogenesis-related adverse events as a potential biomarker of antitumor efficacy in metastatic gastric cancer patients treated with apatinib: a cohort study.

J Hematol Oncol · 2017 · PMC5584332 · PMID 28870253

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The onset of any single AE or any combinations of the three AEs in the first 4 weeks were all statistically significantly associated with prolonged OS, except for the presence of proteinuria (HR 0.81, 95% CI, 0.60, 1.09), which showed a same trend but did not reach statistical significance.

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