Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero.

Acta Neuropathol · 2017 · PMC5587616 · PMID 28755208

Europe PMC DOI

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0.0550

closest p · 1.1× alpha

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boldest claim

The sentences

a strong trendP = 0.055so close (0.05 < p ≤ 0.1)

In the prelimbic cortex, the PSD95-positive synaptic profiles were reduced in layers I and II–III [layer I: t (12) = 7.0, P = 0.00004; layers II–III: t (12) = 4.9, P = 0.0007], with a strong trend in the deep layers [layer V–VI: t (12) = 2.1, P = 0.055].

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