Circulating miR-122 and miR-200a as biomarkers for fatal liver disease in ART-treated, HIV-1-infected individuals.

Sci Rep · 2017 · PMC5589757 · PMID 28883647

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0790

boldest claim

The sentences

on the cusp of significancep = 0.05actually significant

5a ) while miR-200a was on the cusp of significance (r = 0.43, p = 0.05) (Fig. 5b ).

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a clear trendp = 0.079so close (0.05 < p ≤ 0.1)

Furthermore, in the PPPs of these liver cases and controls, the expression of miR-122 was significantly greater (p < 0.01, fold change = 3.3) and miR-200a showed a clear trend towards significance (p = 0.079, fold change = 4.5) in the liver cases compared to their matched controls, while, as expected, let-7e, which showed no association with liver disease in serum, showed no difference in the PPPs.

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