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Randomised Phase 2 study of maintenance linsitinib (OSI-906) in combination with erlotinib compared with placebo plus erlotinib after platinum-based chemotherapy in patients with advanced non-small cell lung cancer.

Br J Cancer · 2017 · PMC5589984 · PMID 28772281

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Other numeric differences in PFS, which did not reach statistical significance, were observed for patients aged ⩾65 years in whom PFS was shorter for the linsitinib/erlotinib treatment arm compared with the placebo/erlotinib arm (127 days vs 171 days; HR=1.30, 95% CI, 0.72–2.34).

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