Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls.

Pancreatic hormone contents versus age In the whole group of ND subjects, insulin, glucagon and somatostatin contents of the pancreas tended to decrease slightly with age, but the correlations did not reach statistical significance (Fig. 2A–C ).

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The slight difference in insulin content (19%) was of the same magnitude as the increase in β-cell mass in OND, but failed to reach significance perhaps because the sample size was too small.

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