At 0.5 h in both hydrogel and tissue, DPV also showed a trend of super-saturation as indicated by a sudden increase in drug concentration and subsequent decline.
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In vitro-ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems.
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We observed a slight trend for PLGA-dominant fibers to enhance sustained release of TFV compared to PCL-dominant fibers ( Figure 5 ).