Barely Significant
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Metoprolol-pridopidine drug-drug interaction and food effect assessments of pridopidine, a new drug for treatment of Huntington's disease.

Br J Clin Pharmacol · 2017 · PMC5595947 · PMID 28449367

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the placebo group did not reach statistical significance although the directionality of the changes suggested a benefit of treatment with pridopidine.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.