Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.

Arthritis Rheumatol · 2017 · PMC5599990 · PMID 28464560

Europe PMC DOI

hedged sentence

0.0525

closest p · 1.0× alpha

0.0525

boldest claim

The sentences

did not reach statistical significanceP = 0.0525so close (0.05 < p ≤ 0.1)

While there was a trend toward reduced osteophyte size with increasing dose of compound 59, this did not reach statistical significance ( P = 0.0525 at 50 mg/kg/day) (Figure 5 B).

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