Twenty-Year Outcome and Association Between Early Treatment and Mortality and Disability in an Inception Cohort of Patients With Rheumatoid Arthritis: Results From the Norfolk Arthritis Register.

Arthritis Rheumatol · 2017 · PMC5600136 · PMID 28425173

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approached significanceno p-value reported

Furthermore, those treated early showed a decrease in HAQ DI scores from baseline to year 10, which approached significance, while those treated later had increased HAQ DI scores at year 10 compared with baseline, again after adjustment for differences in disease severity between groups 30 .

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failed to reach significanceno p-value reported

The SMR for those who were never treated was increased to a similar extent but failed to reach significance.

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a trend toward significanceno p-value reported

The SMR was increased in the ET group (SMR 1.28 [95% CI 1.03, 1.59]) and the LT group (SMR 1.23 [95% CI 1.01, 1.51]), and there was a trend toward significance for the NT group (SMR 1.25 [95% CI 0.99, 1.57]) compared with the general population of Norfolk.

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