nominally significantp<0.05
After adjusting for potential confounders, hsCRP, ICAM, P-selectin, IL-6, TNFR1, and MPO were significantly higher among current smokers at a Bonferroni adjusted p-value threshold (p<0.003), while the following biomarkers did not reach the multiple testing threshold, but were nominally significant (p<0.05): E-selectin, MMP9, and TIMP-2 ( Fig 1 ; Table B in S1 File ).