Differences between groups did not reach statistical significance, although they did trend toward an expected immunosuppressive impact of treatment (mean white blood cell [WBC] counts at day 17: uninfected/no hydroxyurea, 1.4 × 10 7 /ml; infected/no hydroxyurea, 2.4 × 10 7 /ml; uninfected/hydroxyurea at 500 mg/kg/day, 0.8 × 10 7 /ml).
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