highly significantp < 0.001
It decreased significantly between P1 and P2-P4; with GAG content at P1 approximately double that of P2 ( p = 0.004 NRX, p = 0.013 HYP) and highly significant when compared to P3 and P4 (all p < 0.001).
It decreased significantly between P1 and P2-P4; with GAG content at P1 approximately double that of P2 ( p = 0.004 NRX, p = 0.013 HYP) and highly significant when compared to P3 and P4 (all p < 0.001).
The relative gene expression level of ACAN was significantly higher in HYP than NRX of P2 (3.31-fold, p = 0.018) and P4 (3.07-fold, p = 0.01) while HYP stimulated a higher relative gene expression level of COL2A1 in P1 (4.03-fold, approaching significance: p = 0.07), P2 (6.17-fold, p = 0.029) and P4 (8.91 fold: p = 0.085).