Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

Transl Psychiatry · 2017 · PMC5611720 · PMID 28809859

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nominally significantno p-value reported

Mendelian randomisation To further examine the nominally significant genetic correlation between hippocampus and MDD, MR analysis was performed to test for a directional association between hippocampal volume and MDD.

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