HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings.

However, specific processes were detected as highly significant by HTS-Net, such as ‘viral process’ (16 genes– 9 found by Chia et al.).

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Other specific enrichments found in Chia’s secondary screening were detected at the limit of significance at FDR 0.05 by HTS-Net, such as ‘oligodendrocyte development’, ‘cellular response to stimulus’ and processes related to ‘negative regulation of transcription’ and ‘negative regulation of translational initiation in response to stress’.

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Tai did not initially retain PIP5K1A, which has a mildly significant z-score (-1.820).

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