Barely Significant
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A chronological study of the bacterial pathogen changes in acute neonatal bacterial conjunctivitis in southern China.

BMC Ophthalmol · 2017 · PMC5615761 · PMID 28950852

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a clear trendno p-value reported
However, the proportion of cases with Mycobacterium xerosis conjunctiva did not show a clear trend during those years.

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a decreasing trendno p-value reported
Interestingly, the proportion of cases with Gram-positive bacteria showed a decreasing trend during the 15-year period.

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an overall trendno p-value reported
Results From the analysis of the bacterial pathogens in 485 cases of acute neonatal conjunctivitis patients from 2002 to 2016 in Southern China, there is an overall trend of decreasing detection of Gram-positive bacteria and increasing detection of Gram-negative bacteria from the conjunctival sac secretions.

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an increasing trendno p-value reported
When the year-by-year data from those 15 years was compared, the proportion of cases involving Staphylococcus epidermidis and Staphylococcus saprophyticus experienced an increasing trend (increased by ~60%), whereas the proportion of cases with Staphylococcus aureus and Hemolytic streptococcus ( alpha- and beta- ) showed a decreasing trend in most of the years (decreased by ~30% and ~20% respectively) (Fig. 1b ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.