Exposure to perfluoroundecanoic acid (PFUnDA) accelerates insulitis development in a mouse model of type 1 diabetes.

Toxicol Rep · 2016 · PMC5616085 · PMID 28959590

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did not reach statistical significanceno p-value reported

Further, immunohistological analysis of the number of tissue resident macrophages in pancreatic islets prior to insulitis (in islets with insulitis grade 0) indicated a decreased number of F4/80+ macrophages with increasing PFUnDA exposure at both 7 and 11 weeks of age, although it did not reach statistical significance ( Fig. 2 a).

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