[ 15 ] found better severity and interference scores in the Brief Pain Inventory (BPI) in patients receiving zoledronic acid plus everolimus compared to those receiving everolimus alone, although the difference did not reach statistical significance ( P = 0.054 and 0.055, respectively), whereas no detectable effect was seen in the Functional Assessment of Cancer Therapy–Bone Pain scores ( P = 0.53).
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Comparative efficacy and safety of bone-modifying agents for the treatment of bone metastases in patients with advanced renal cell carcinoma: a systematic review and meta-analysis.
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