Notch2 blockade enhances hematopoietic stem cell mobilization and homing.

Haematologica · 2017 · PMC5622863 · PMID 28729299

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Granulocyte numbers derived from mobilized and Notch2-blocked HSPCs were significantly higher than those derived from control cells by ten and 13 weeks after transplantation, while lymphocytes contributed by Notch2-blocked HSPCs also showed a trend of increase ( Figure 4C ).

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