A Masked, Randomized, Phase 3 Comparison of Triple Fixed-Combination Bimatoprost/Brimonidine/Timolol versus Fixed-Combination Brimonidine/Timolol for Lowering Intraocular Pressure.

J Ophthalmol · 2017 · PMC5625812 · PMID 29057117

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highly significantno p-value reported

In the current study, the results of the mean IOP responder analysis showed that substantially more patients in the TFC group reached the very low IOP levels of ≤13, and even ≤12 mmHg, and the results were highly significant.

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did not reach statistical significanceno p-value reported

Twice as many patients on DFC reported somnolence, although the difference did not reach statistical significance ( Table 4 ).

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