Although small iIELs from Xbp1 T-ΔIEC mice did not contain higher frequencies of T cells and showed a trend toward lower overall frequencies of αβ + T cells, we observed a significant increase in γδ + T cells ( Fig. 4 C ).
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Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.
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