Maternal intake of grape seed procyanidins during lactation induces insulin resistance and an adiponectin resistance-like phenotype in rat offspring.

Results GSPE supplementation increased the circulating levels of NEFAs and total adiponectin in dams GSPE dams showed decreased liver weight (p = 0.032, Student’s t test) and a clear trend toward lower body weight gain compared with the VEH animals (p = 0.061, Student’s t test), which could be attributed to a decreased daily energy intake (p = 0.013, Student’s t test) (Table 2 ).

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