Multicenter, real-life experience with checkpoint inhibitors and targeted therapy agents in advanced melanoma patients in Switzerland.

Melanoma Res · 2017 · PMC5633326 · PMID 28509765

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a nonsignificant trendP =0.06so close (0.05 < p ≤ 0.1)

We observed a nonsignificant trend toward an improved survival in patients with brain metastases treated with TT ( P =0.06) and a significant survival benefit in those treated with IT+TT.

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did not reach statistical significanceno p-value reported

Although survival was numerically different in our IT study cohort within LDH low and high patients, the difference did not reach statistical significance, probably due to the low number of IT-treated.

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