Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria.

The correlation between 59 Fe-transferrin accumulation and endogenous transferrin excretion did not reach statistical significance in either group, however the NZB/W mice that displayed high %ID of 59 Fe-transferrin in the kidneys uniformly also displayed high urinary excretion of endogenous transferrin (Fig. 3F ).

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