Polymorphism IL-1RN rs419598 reduces the susceptibility to generalized periodontitis in a population of European descent.

PLoS One · 2017 · PMC5638498 · PMID 29023524

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did not reach statistical significanceno p-value reported

The likelihood of GAgP was significantly higher versus controls in patients with polymorphisms in IL-1RN and IL-1A and/or IL-1B (OR = 9.49; 95%CI [1.37–65.62]), but it was lower in comparison to those with polymorphisms in IL-1A and/or IL-1B alone (OR = 12.49; 95%CI [2.25–69.43]) The effect of the IL-1RN polymorphism alone did not reach statistical significance (OR = 0.606; 95%CI [0.21–1.75]).

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