EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.

Nat Commun · 2017 · PMC5638898 · PMID 29026085

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did not reach statistical significanceno p-value reported

We noted that reduction of S phase GC B cells in Ezh2 fl/fl ;Cγ1-cre organoids did not reach statistical significance (Fig. 4d ), perhaps because of incomplete CRE-mediated excision of Ezh2 in the residual GC B cells.

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