After 19-days there was a 5.7-fold inhibition in tumor volume in the A1 −M/−M animals relative to WT controls (p=0.02), and a similar trend toward inhibition in DKO animals, although the numbers did not reach statistical significance (Figure 3 ).
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Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.
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