Barely Significant
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Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.

Mol Metab · 2017 · PMC5641599 · PMID 29031731

1
hedged sentence
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)
Although this result did not reach statistical significance (p = 0.09) when compared to placebo, weight loss from baseline was significantly reduced (p < 0.0001).

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