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The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma.

PLoS One · 2017 · PMC5643071 · PMID 29036186

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The fact that better OS in cases with AA genotype did not reach statistical significance could be attributed to the small sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.