Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.

PLoS One · 2017 · PMC5643135 · PMID 29036218

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quite significantno p-value reported

However, the difference between the K d and IC 50 values for each compound is quite significant (IC 50 ’s are on average ~10-fold lower than the K d ’s; Fig 2 and Table 3 ).

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