Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.

Acta Neuropathol · 2017 · PMC5645450 · PMID 28612290

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a strong trendno p-value reported

We also noted a strong trend toward down-regulation of Cd33 in the DG of Tyrobp − / − mice (log FC = −0.9, FDR = 0.077).

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