HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD.

Sci Rep · 2017 · PMC5645472 · PMID 29042644

Europe PMC DOI

hedged sentence

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

showed a trendP = 0.077so close (0.05 < p ≤ 0.1)

mRNA levels of Chrebp and the canonical ChREBP target gene liver pyruvate kinase ( Lpk ) were increased in both Vpr mouse models compared to their respective control mice; the mRNA level of Srebp1c was not significantly increased in Vpr-Tg compared to WT mice but showed a trend (P = 0.077) towards increase in sVpr-treated compared to vehicle-treated mice (Fig. 2B,D ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.