Neutrophil lymphocyte ratio and duration of prior anti-angiogenic therapy as biomarkers in metastatic RCC receiving immune checkpoint inhibitor therapy.

J Immunother Cancer · 2017 · PMC5646127 · PMID 29041991

Europe PMC DOI

hedged sentences

0.0730

closest p · 1.5× alpha

0.0730

boldest claim

The sentences

marginally significantp = 0.073so close (0.05 < p ≤ 0.1)

This factor remained a statistically significant predictor of outcome in the multivariable PFS analysis(HR, 2.288; 95% CI, 1.09 to 4.79; p = 0.028) and marginally significant in the multivariable OS analysis (HR, 2.913; 95% CI, 0.90 to 9.39; p = 0.073).

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did not reach statistical significanceno p-value reported

The p -values did not reach statistical significance for prediction of clinical outcomes with ICI therapy within the Heng or MSKCC prognostic categories.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.