Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.

Nominally significant parental genetic effects were found between the SNPs rs11191548 ( CYP17A1 ) (paternal, β = 2.78±1.49, P = 6.1×10 −2 for SBP and β = 3.60±1.24, P = 3.7×10 −3 for DBP), rs17367504 ( MTHFR ) (paternal, β = 2.42±0.93, P = 9.3×10 −3 for SBP and β = 1.89±0.80, P = 1.8×10 −2 for DBP and maternal, β = -1.32±0.60, P = 2.9×10 −2 and β = -1.97±0.77, P = 1.0×10 −2 , for SBP and DBP respectively) and child blood pressure.

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