PCDH9 acts as a tumor suppressor inducing tumor cell arrest at G0/G1 phase and is frequently methylated in hepatocellular carcinoma.

Mol Med Rep · 2017 · PMC5647006 · PMID 28791409

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did not reach statistical significanceP>0.05actually significant

In addition, 22% of the HCC tumor-derived tissues tested (24/111 paired samples successfully analyzed) indicated higher levels of methylation in the tumor tissue sample compared with that observed in the corresponding adjacent non-tumor tissues and normal liver tissues, however such differences did not reach statistical significance (P>0.05; Fig. 1E ).

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