Effectiveness and patient safety of platelet aggregation inhibitors in the prevention of cardiovascular disease and ischemic stroke in older adults - a systematic review.

However, these results did not reach statistical significance (odds ratio (OR) 3.23; 95% CI: 0.56–18.66).

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In the older participants (≥65 years), the reduction of major cardiovascular events was marginally significant (≥65 years RR: 0.90; 95% CI: 0.83–0.98), whereas the risk of major bleeding events under a treatment with ASA plus clopidogrel vs.

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