Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression.

PLoS One · 2017 · PMC5648231 · PMID 29049348

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The CMS+fluoxetine group showed a trend of decrease in the plasma level of IL-1β from day 0 to day 120, with significant decrease in IL-1β level on day (60 (206.06±78.41) pg/ml, p <0.05) and day 120 ((141.05±56) pg/ml, p <0.05) as compared to its baseline level on day 0 (344.31±114.33) pg/ml via Wilcoxon signed-rank test.

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