Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor.

Alzheimers Dement (N Y) · 2016 · PMC5651349 · PMID 29067308

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showed a trendno p-value reported

The Aβ-lowering effect was persistent over 36 hours for the highest doses (90 and 150 mg), whereas participants treated with lower doses showed a trend for return to baseline 36 hours after dose.

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