Adding serial NT-proBNP to the model containing age, sex, systolic blood pressure and eGFR and NYHA class provided a substantial increase in C‐index from 0.76 (CI 0.66–0.86) to 0.84 (0.74–0.93), although this did not reach statistical significance ( p = 0.26).
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In search of an efficient strategy to monitor disease status of chronic heart failure outpatients: added value of blood biomarkers to clinical assessment.
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