In the phase III AVAGAST study, high VEGF-A (HR, 0.72; 95% CI, 0.57 to 0.93) and low neuropilin-1 (HR, 0.75; 95% CI, 0.59 to 0.97) showed a trend for improved OS; however, these findings were only found to be statistically significant in patients from non-Asian regions [ 61 ].
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Anti-angiogenic Therapy in Patients with Advanced Gastric and Gastroesophageal Junction Cancer: A Systematic Review.
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