Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Acta Neuropathol Commun · 2017 · PMC5663045 · PMID 29084603

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did not reach statistical significanceno p-value reported

It is worth noting that within the limitations of sample size, we observed a trend towards an increase in the mutational burden at recurrence that did not reach statistical significance despite the use of TMZ as adjuvant therapy in 10/16 (63%) pHGGs.

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