Although not statistically significant, a tendency toward increased mortality because of stroke and cerebral infarction were indicated in the ≤19 years group. While no significant difference was apparent, there was an evident tendency toward a U-shaped relationship between age at first birth and the mortality because of cancer and cardiovascular diseases.
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Age at first birth and long-term mortality for mothers: the Ohsaki cohort study.
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The sentences
With regard to stroke, a tendency for an increased risk with higher age at first birth has been reported [ 20 ], whereas a decreasing trend has been found for coronary heart disease [ 21 ].