TDP-43 accelerates age-dependent degeneration of interneurons.

Sci Rep · 2017 · PMC5668320 · PMID 29097807

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showed a trendno p-value reported

While the heterozygous TDP-43 Tg mice showed a trend of a decrease in body weight with increasing age, they did not show obvious signs of paralysis for over 2 years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.