The immunological personality of close relatives of SLE patients.

Lupus · 2017 · PMC5673006 · PMID 28534426

Europe PMC DOI

hedged sentences

0.0050

closest p · 0.1× alpha

0.0800

boldest claim

The sentences

highly significantp < 0.005actually significant

There was for female relatives a highly significant negative correlation between NK cell numbers and IgM ( r = −0.54, p < 0.005) and a weaker negative correlation between B cells and IgM (−0.40, p < 0.05).

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approached significancep < 0.08so close (0.05 < p ≤ 0.1)

There was a strong negative correlation with NKT cell numbers in the male relative group (−0.69, p < 0.01) while a similar relationship in the female relatives approached significance (−0.34, p < 0.08).

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may be significantno p-value reported

It may be significant that reduced levels of the regulatory cytokines TGF-β and IL-10 have been observed in relatives. 13 In the study by Wither et al. 12 abnormalities were demonstrated in first-degree relatives of SLE patients relating to the proportion of various B and T cell subsets and in the frequency of antinuclear antibody (ANA) positivity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.