Innovative intraoral cooling device better tolerated and equally effective as ice cooling.

Cancer Chemother Pharmacol · 2017 · PMC5676821 · PMID 28975429

Europe PMC DOI

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a clear trendno p-value reported

Regarding the adverse events noted, there is a clear trend towards design-related problems with the cooling device, whereas cold sensations and numbness accounted for the majority of the problems experienced with the ice chips.

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